Glypican-3 (Gpc3)
Body size (weight)
Cis-regulatory,
Unknown
Mus musculus
house mouse - (species)
Domesticated
Linkage Mapping
Oliver F; Christians JK; Liu X ; et al. (2005)
Regulatory variation at glypican-3 underlies a major growth QTL in mice.
GP00000407
Gpc3
Q8CFZ4
Physiology
unknown; possible 3'UTR variation
Mus musculus
house mouse - (species)
Mus musculus
house mouse - (species)
Glypican-3 (Gpc3)
Mus musculus
house mouse - (species)
Published - Accepted by Curator
GPR133
Body size (weight)
Cis-regulatory,
Unknown
Mus musculus
house mouse - (species)
Domesticated
Association Mapping
Chan YF; Jones FC; McConnell E ; et al. (2012)
Parallel selection mapping using artificially selected mice reveals body weight control loci.
GP00000411
ADGRD1
Q6QNK2
Physiology
unknown
Mus musculus
house mouse - (species)
Mus musculus
house mouse - (species)
GPR133
Mus musculus
house mouse - (species)
Published - Accepted by Curator
growth hormone receptor (GHR)
Body size (weight)
Coding,
SNP
Canis lupus familiaris
dog - (subspecies) D
Domesticated
Association Mapping
Rimbault M; Beale HC; Schoenebeck JJ ; et al. (2013)
Derived variants at six genes explain nearly half of size reduction in dog breeds.
GP00001475
GHR
Q9TU69
Morphology
G>A in exon 5 p.E191K in extracellular domain
Canis lupus
gray wolf - (species)
Canis lupus familiaris
dog - (subspecies) D
growth hormone receptor (GHR)
Canis lupus familiaris
dog - (subspecies)
Published - Accepted by Curator
growth hormone receptor (GHR)
Body size (weight)
Coding,
SNP
Canis lupus familiaris
dog - (subspecies) D
Domesticated
Association Mapping
Rimbault M; Beale HC; Schoenebeck JJ ; et al. (2013)
Derived variants at six genes explain nearly half of size reduction in dog breeds.
GP00001476
GHR
Q9TU69
Morphology
C>T in exon 5 p.P177L in extracellular domain
Canis lupus
gray wolf - (species)
Canis lupus familiaris
dog - (subspecies) D
growth hormone receptor (GHR)
Canis lupus familiaris
dog - (subspecies)
Published - Accepted by Curator
IGF2BP1
Body size (weight)
Cis-regulatory,
Unknown
Anas platyrhynchos
mallard - (species) D
Domesticated
Linkage Mapping
Zhou Z; Li M; Cheng H ; et al. (2018)
An intercross population study reveals genes associated with body size and plumage color in ducks.
GP00002128
IGF2BP1
O42254
Morphology
We found that the phenotypic values of body size related traits together with IGF2BP1 expression levels were successfully fine-mapped of the causal variation in an ~100-kb region (chr28: 4,413,785-4,513,671) located on the 148 kb upstream of the IGF2BP1 gene
Anas platyrhynchos
mallard - (species)
Anas platyrhynchos
mallard - (species) D
IGF2BP1
Anas platyrhynchos
mallard - (species)
Published - Accepted by Curator
Insulin-like growth factor receptor 1 (IGF1R)
Body size (weight)
Coding,
SNP
Homo sapiens
human - (species) D
Domesticated
Candidate Gene
Rimbault M; Beale HC; Schoenebeck JJ ; et al. (2013)
Derived variants at six genes explain nearly half of size reduction in dog breeds.
GP00001479
IGF1R
P08069
Morphology
G>A p.R204H in exon 2
Canis lupus
gray wolf - (species)
Homo sapiens
human - (species) D
Insulin-like growth factor receptor 1 (IGF1R)
Homo sapiens
human - (species)
Published - Accepted by Curator
miR-15a-16
Body size (weight)
Cis-regulatory,
Insertion
N
Gallus gallus
chicken - (species) D
Domesticated
Linkage Mapping
Jia X; Lin H; Nie Q ; et al. (2016)
A short insertion mutation disrupts genesis of miR-16 and causes increased body weight in domesticat[...]
GP00002247
Morphology
54-bp insertion introducing splicing site that affect the mature transcript N
Gallus gallus
chicken - (species)
Gallus gallus
chicken - (species) D
miR-15a-16
Gallus gallus
chicken - (species)
Published - Accepted by Curator
Prolactin releasing hormone receptor (Prlhr/GPR10)
Body size (weight)
Cis-regulatory,
Unknown
Mus musculus
house mouse - (species)
Domesticated
Association Mapping
Chan YF; Jones FC; McConnell E ; et al. (2012)
Parallel selection mapping using artificially selected mice reveals body weight control loci.
GP00000928
PRLHR
P49683
Physiology
unknown
Mus musculus
house mouse - (species)
Mus musculus
house mouse - (species)
Prolactin releasing hormone receptor (Prlhr/GPR10)
Mus musculus
house mouse - (species)
Published - Accepted by Curator
RB1
Body size (weight)
Body size (bone length)
Unknown,
Unknown
Gallus gallus
chicken - (species)
Domesticated
Linkage Mapping
Zhang H; Liu SH; Zhang Q ; et al. (2011)
Fine-mapping of quantitative trait loci for body weight and bone traits and positional cloning of th[...]
GP00000957
Morphology
Morphology
unknown
Gallus gallus
chicken - (species)
Gallus gallus
chicken - (species)
RB1
Gallus gallus
chicken - (species)
Published - Accepted by Curator
SMAD family member 2 (SMAD2)
Body size (weight)
Cis-regulatory,
Deletion
Homo sapiens
human - (species) D
Domesticated
Association Mapping
Rimbault M; Beale HC; Schoenebeck JJ ; et al. (2013)
Derived variants at six genes explain nearly half of size reduction in dog breeds.
GP00001477
SMAD2
E2RP23
Morphology
9.9 kb deletion 24-kb dowstream from coding region
Canis lupus
gray wolf - (species)
Homo sapiens
human - (species) D
SMAD family member 2 (SMAD2)
Homo sapiens
human - (species)
Published - Accepted by Curator
stanniocalcin 2 (STC2)
Body size (weight)
Cis-regulatory,
SNP
Homo sapiens
human - (species) D
Domesticated
Association Mapping
Rimbault M; Beale HC; Schoenebeck JJ ; et al. (2013)
Derived variants at six genes explain nearly half of size reduction in dog breeds.
GP00001478
STC2
O76061
Morphology
T>A 20-kb downstream from coding region
Canis lupus
gray wolf - (species)
Homo sapiens
human - (species) D
stanniocalcin 2 (STC2)
Homo sapiens
human - (species)
Published - Accepted by Curator